Lot-matched COA on file KYN-2T
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A synthetic peptide of 39 amino acid residues carrying a C20 fatty diacid chain attached through a linker to a lysine side chain. The sequence also carries alpha-aminoisobutyric acid residues at two positions in place of the residues found in the corresponding native sequences.
These substitutions are structural. The acylation promotes reversible association with serum albumin; the aminoisobutyric acid residues remove recognition sites for cleavage by dipeptidyl peptidase-4.
COMPOSITION
39 amino acid residues, side-chain acylated · Formula C225H348N48O68 · MW 4,813.53 g/mol · CAS 2023788-19-2
ANALYTICAL SPECIFICATION
Identity confirmed by mass spectrometry against the theoretical molecular weight. Purity by reverse-phase HPLC at 214 nm, reported as area percent. Each lot ships with a certificate of analysis matched to its lot number.
FORM AND STORAGE
White to off-white lyophilized powder. Store lyophilized, protected from light. Acylated peptides of this size are prone to aggregation; keep the vial sealed.
Supplied for laboratory research use only. Not for human or veterinary use. No preparation, measurement, handling or application instructions are provided.
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Analytical specifications
| Chemical name | KYN-2T |
|---|---|
| Class | Synthetic acylated peptide; 39 residues, C20 fatty diacid side-chain modification |
| Sequence | Tyr-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-Aib-Leu-Asp-Lys-Ile-Ala-Gln-Lys[γ-Glu-(AEEA)₂-C20 diacid]-Ala-Phe-Val-Gln-Trp-Leu-Ile-Ala-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH₂ |
| Molecular weight | 4,813.53 g/mol |
| Molecular formula | C₂₂₅H₃₄₈N₄₈O₆₈ |
| CAS number | 2023788-19-2 |
| Purity | ≥ 99.8% (HPLC) |
| Identity | Confirmed by mass spectrometry |
| Form | Lyophilized powder |
| Amount | 10 mg per vial |
| Storage | Store lyophilized, protected from light |
| Current lot | KR260709A |
