Lot-matched COA on file TB-500
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Thymosin Beta-4 is a naturally occurring peptide of 43 amino acid residues, present across mammalian cell types and among the more abundant intracellular peptides of its class.
A NOTE ON NAMING
The designation TB-500 is applied in this category to two chemically distinct materials: the full-length 43-residue peptide, and a synthetic seven-residue fragment of its sequence, Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln. The two differ substantially in molecular weight and carry different CAS registry numbers. Suppliers frequently use the names interchangeably; they are not interchangeable.
This item is supplied to the specification given in the analytical table on this page. Confirm the molecular weight and CAS number against the certificate of analysis for the lot you receive before use in any comparative work.
Full-length Thymosin Beta-4 · CAS 77591-33-4 · MW 4,963.44 g/mol
Seven-residue fragment · CAS 885340-08-9 · MW 889.02 g/mol
ANALYTICAL SPECIFICATION
Identity confirmed by mass spectrometry against the theoretical molecular weight. Purity by reverse-phase HPLC at 214 nm, reported as area percent. Each lot ships with a certificate of analysis matched to its lot number.
FORM AND STORAGE
White to off-white lyophilized powder. Store lyophilized, protected from light.
Supplied for laboratory research use only. Not for human or veterinary use. No preparation, measurement, handling or application instructions are provided.
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Analytical specifications
| Chemical name | TB-500 |
|---|---|
| Class | Synthetic 43-amino-acid, N-terminally acetylated peptide; full-length thymosin beta-4 |
| Sequence | Ac-SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES-OH |
| Molecular weight | 4963.44 g/mol |
| Molecular formula | C₂₁₂H₃₅₀N₅₆O₇₈S |
| CAS number | 77591-33-4 |
| Purity | ≥ 99.62% (HPLC) |
| Identity | Confirmed by mass spectrometry |
| Form | Lyophilized powder |
| Amount | 10 mg per vial |
| Storage | Store lyophilized, protected from light |
| Current lot | KR260709A |



